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Preoperative dextrose does not affect spinal-induced hypotension in elective Cesarean section
1Department of Anaesthesia, BC Women's Hospital and Health Centre, Vancouver, Canada.
Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie
|November 24, 1999
Summary
Preoperative intravenous dextrose does not reduce the incidence or ease of treating spinal-induced hypotension in Cesarean sections. This study found no significant difference in hypotension rates or vasopressor needs between groups receiving dextrose or saline.
Area of Science:
- Anesthesiology
- Obstetrics
- Pharmacology
Background:
- Spinal anesthesia for Cesarean section can induce hypotension.
- Preventive measures are crucial to maintain maternal and fetal well-being.
Purpose of the Study:
- To investigate the effect of preoperative intravenous dextrose on spinal-induced hypotension during elective Cesarean sections.
- To assess if dextrose administration impacts the ease of hypotension management.
Main Methods:
- Prospective, double-blind, randomized study involving 119 parturients.
- Groups received either 5% dextrose in normal saline or normal saline intravenously for two hours pre-delivery.
- Spinal anesthesia induced with bupivacaine, fentanyl, and morphine; hypotension defined and treated with fluids/vasopressors.
Main Results:
- No significant difference in the rate of hypotension between the dextrose and saline groups (P = 0.272).
- No difference in vasopressor requirements (ephedrine) between the groups.
- All hypotensive episodes were managed effectively with standard fluid and vasopressor therapy.
Conclusions:
- Routine preoperative intravenous dextrose administration does not alter the incidence of spinal-induced hypotension.
- Dextrose infusion does not simplify the treatment of hypotension in this setting.
- Current practice of dextrose administration for this purpose may not be beneficial.