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Calreticulin: one protein, one gene, many functions

M Michalak1, E F Corbett, N Mesaeli

  • 1MRC Group in Molecular Biology of Membranes, Department of Biochemistry, University of Alberta, 3-56 Medical Sciences Building, Edmonton, Alberta, Canada T6G 2H7. Marek.Michalak@ualberta.ca

The Biochemical Journal
|November 24, 1999
PubMed
Summary

Calreticulin, an endoplasmic reticulum (ER) protein, acts as a chaperone for protein synthesis and regulates calcium (Ca2+) homeostasis. This versatile protein influences numerous cellular functions within and outside the ER.

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