Related Experiment Video
Updated: Jul 28, 2026

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel
Published on: June 29, 2015
Mesenteric infarction due to combined protein C deficiency and prothrombin 20210 defects
C J Mainwaring1, M Makris, W E Thomas
1Department of Haematology, Royal Hallamshire Hospital, Sheffield, UK.
Abstract:
The prothrombin gene mutation, 20210A, a guanine to adenine substitution at nucleotide position 20210, has recently been described as an additional risk factor for venous thromboembolic disease. We describe the case of a patient with combined heterozygous prothrombin 20210A mutation and type 1 protein C deficiency who presented with massive mesenteric venous infarction of his small bowel and survived following the use of protein C concentrate and extensive small bowel resection.
Related Concept Videos
Myocarditis I: Introduction
Venous Thrombosis I: Introduction
Ischemic Stroke l: Introduction
Chronic Pancreatitis II: Pathophysiology

