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Updated: Oct 18, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Differential effects of individual trans fatty acid isomers on lipoprotein assembly and metabolism
1School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Québec, Canada.
Abstract:
Recent findings indicate that certain (t-C18:1 delta 9) but not all (t-C16:1 delta 9 and t-C18:1 delta 11) trans fatty acid isomers influence intestinal lipoprotein secretion. A mechanism is suggested that appears to be sensitive to properties associated not only with geometric configuration but also with fatty acid chain length and double bond position. This mechanism could explain, in part, the conflicting results seen among studies investigating the effects of total dietary trans fatty acids on serum lipid and lipoprotein concentrations.
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