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G banding in cytogenetic study of hemoblastoses
Humangenetik
|January 1, 1975
Abstract:
G banding was used in the study of the karyotype of malignant cells in 10 patients: 5 with CML (3 in blastic crisis), 3 with AL and 2 with lymphosarcomas. In all cases of CML 22q-- (Ph1-chromosome) and 9q+ were present in leukemic cells. An i(17q) was observed in the karyotype of 2 out of 3 patients in blastic crisis of CML. In AL and lymphosarocmas small chromosome rearrangements were revealed and the origin of marker chromosomes could be established by the aid of G banding.