Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Identification of intraocular lens materials using confocal Raman spectroscopy.

E E Smit1, R J Erckens, F Hendrikse

  • 1University of Texas Medical Branch, Galveston, USA.

Journal of Cataract and Refractive Surgery
|November 24, 1999
PubMed
Summary

This study developed a noninvasive Raman spectroscopy method to identify intraocular lens (IOL) materials. The Conforam system successfully differentiated silicone, PMMA, acrylic, and hydrogel IOLs in vitro.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In vivo optoacoustic temperature imaging for image-guided cryotherapy of prostate cancer.

Physics in medicine and biology·2018
Same author

Molecular characterization of environmental Cladosporium species isolated from Iran.

Current medical mycology·2018
Same author

Proteolytic activity and cooperative hemolytic effect of dermatophytes with different species of bacteria.

Current medical mycology·2017
Same author

Molecular identification and <i>in-vitro</i> antifungal susceptibility testing of <i>Candida</i> species isolated from patients with onychomycosis.

Current medical mycology·2017
Same author

Aspergillus tubingensis and Aspergillus niger as the dominant black Aspergillus, use of simple PCR-RFLP for preliminary differentiation.

Journal de mycologie medicale·2016
Same author

Dental Erosion in Patients with Gastroesophageal Reflux Disease (GERD) in a Sample of Patients Referred to the Motahari Clinic, Shiraz, Iran.

Journal of dentistry (Shiraz, Iran)·2014

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Spectroscopy

Background:

  • Intraocular lenses (IOLs) are crucial for vision restoration after cataract surgery.
  • Accurate identification of IOL materials is important for understanding biocompatibility and long-term stability.
  • Current methods for IOL material identification may be invasive or destructive.

Purpose of the Study:

  • To develop and validate a noninvasive technique for identifying different intraocular lens (IOL) materials.
  • To assess the efficacy of laser confocal Raman spectroscopy for IOL material characterization.
  • To establish a reliable method for distinguishing between common IOL materials.

Main Methods:

  • Utilized a laser confocal Raman spectroscopy system (Conforam) for spectral analysis.

Related Experiment Videos

  • Examined four distinct IOL materials: silicone, poly(methyl methacrylate) (PMMA), acrylic, and hydrogel.
  • Acquired Raman spectra in both lower and higher spectral regions (299.1–1833.7 cm⁻¹ and 2633.8–3819.6 cm⁻¹).

    • Main Results:

    • Each IOL material exhibited a unique spectral signature in both analyzed regions.
    • Distinct peaks and profiles were observed for most materials, even with low laser power (1 mW) and short exposure (1 second).
    • The Conforam system effectively distinguished between all tested IOL materials based on their Raman spectra.

    Conclusions:

    • Laser confocal Raman spectroscopy with the Conforam system provides a noninvasive method for differentiating IOL materials.
    • This technique offers a fast, safe, and reliable approach for identifying implanted IOL materials.
    • Raman spectroscopy holds potential for assessing the stability of IOL materials and coatings.