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Magnetic resonance imaging and angiography in cerebral fungal vasculitis
C Christophe1, N Azzi, B Bouché
1Department of Radiology, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium.
Abstract:
We report on an 11-year old girl treated for leukemia who developed infarcts in the right lentiform nucleus and temporal lobe. Magnetic resonance angiography (MRA) showed mild intraluminal irregularities in the right carotid syphon and stenosis of the right proximal middle cerebral artery, suggesting vasculitis. Magnetic resonance imaging (MRI) follow-up showed evolution of the initial infarct into an abscess. Stereotactic biopsy disclosed filaments of aspergillus. This report emphasizes the fact that cerebral aspergillosis should be considered if MRA and MRI are indicative of vasculitis and cerebral infarction in immunosuppressed children.
Insights
Cerebral aspergillosis, a fungal infection, can mimic vasculitis in immunosuppressed children. Early diagnosis is crucial for effective treatment of invasive fungal infections in immunocompromised patients.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatric Oncology
Background:
- Immunosuppressed children undergoing leukemia treatment are susceptible to opportunistic infections.
- Cerebral infarcts can present with varied etiologies in pediatric patients.
- Vasculitis is a potential cause of stroke in immunocompromised individuals.