Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gardner's syndrome.

A Halse, B Roed-Petersen, K Lund

    Journal of Oral Surgery (American Dental Association : 1965)
    |September 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Gardner's syndrome, a rare genetic disorder, can present initially with facial osteomas. A definitive diagnosis requires the subsequent development of colonic polyposis, as seen in this case study.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Physical activity increases survival after heart valve surgery.

    Heart (British Cardiac Society)·2016
    Same author

    Plasma levels of marine n-3 fatty acids and cardiovascular risk markers in renal transplant recipients.

    European journal of clinical nutrition·2016
    Same author

    Intravenous Infusion of Nitroglycerine Leads to Increased Permeability on Dynamic Contrast-Enhanced MR Imaging in Pig Brains.

    AJNR. American journal of neuroradiology·2015
    Same author

    The effects of dexmedetomidine on postoperative pain.

    Anaesthesia·2015
    Same author

    Evaluation of the effects of single-nucleotide polymorphisms in CYP3A4 and CYP4F2 on stable phenprocoumon and acenocoumarol maintenance doses: comment.

    Journal of thrombosis and haemostasis : JTH·2014
    Same author

    EZH2 in normal and malignant hematopoiesis.

    Leukemia·2013

    Area of Science:

    • Medical Genetics
    • Oncology
    • Surgical Pathology

    Background:

    • Gardner's syndrome is an autosomal dominant disorder characterized by the triad of familial adenomatous polyposis, osteomas, and soft tissue tumors.
    • Early diagnosis of Gardner's syndrome is crucial for timely intervention and management of associated complications, particularly colorectal cancer.

    Purpose of the Study:

    • To present a case study illustrating the diagnostic challenges and eventual confirmation of Gardner's syndrome.
    • To highlight the importance of long-term patient monitoring for the development of characteristic symptoms.

    Main Methods:

    • Clinical case presentation and follow-up.
    • Review of diagnostic criteria for Gardner's syndrome.

    Main Results:

    Related Experiment Videos

    • A 22-year-old female initially presented with multiple osteomas of the facial skeleton.
    • Other characteristic symptoms of Gardner's syndrome were absent during the initial examination.
    • The diagnosis was confirmed four years later upon the development of colonic polyposis.

    Conclusions:

    • Facial osteomas alone may not be sufficient for an early diagnosis of Gardner's syndrome.
    • The development of colonic polyposis is a critical diagnostic marker for Gardner's syndrome.
    • Longitudinal observation is essential in cases with suggestive but incomplete initial findings.