Related Experiment Video
Updated: May 18, 2026

10:31
Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
[Peanut anaphylaxis: the problem of hidden allergens]
S Borelli1, M D Anliker, B Wüthrich
1Allergiestation, UniversitätsSpital Zürich.
Deutsche Medizinische Wochenschrift (1946)
|November 26, 1999
Summary
Severe peanut allergy can cause recurrent anaphylaxis from hidden peanuts in various foods, including Asian and bakery products. Patients need education on avoidance and emergency preparedness for accidental ingestion.
Area of Science:
- Allergy and Immunology
- Food Science
Background:
- Recurrent anaphylaxis presents a diagnostic challenge, particularly when food triggers are not immediately obvious.
- Peanut allergy is a common and potentially severe food allergy.
Observation:
- Three patients experienced recurrent anaphylactic reactions after consuming diverse food items.
- All patients were diagnosed with severe peanut allergy, confirmed via skin prick tests or serological testing for specific IgE.
Findings:
- Anaphylaxis in these patients was attributed to the ingestion of peanuts concealed within various foods.
- Peanuts are frequently used in American and Asian cuisines and can be found in processed foods due to their low cost, protein content, and thickening properties.
Implications:
- Accidental ingestion of hidden peanuts is a significant risk for individuals with peanut allergy.
- Clear labeling and consumer awareness are crucial to prevent severe allergic reactions.
- Patients with peanut allergy require comprehensive education on potential sources of hidden peanuts and emergency management strategies.
Related Concept Videos
Cross-reactivity
Overview
Allergic Reactions
Overview
Allergic Drug Reactions
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Hypersensitivities
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

