Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breast cancer screening.

B E Sirovich1, H C Sox

  • 1Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, Vermont, USA.

The Surgical Clinics of North America
|November 26, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Registration of clinical trials: a statement from the International Committee of Medical Journal Editors].

Nederlands tijdschrift voor geneeskunde·2004
Same author

The burden of prevention: downstream consequences of Pap smear testing in the elderly.

Journal of medical screening·2004
Same author

Commentary of "Hospitalists and the doctor-patient relationship".

The Journal of legal studies·2003
Same author

[Sponsorship, authorship and accountability].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2002
Same author

Sponsorship, authorship, and accountability.

Obstetrics and gynecology·2002
Same author

Sponsorship, authorship and accountability.

Lakartidningen·2001

Screening mammography reduces breast cancer mortality, especially for women aged 50-69. Benefits for younger women (40-49) are less clear, necessitating individualized discussions about risks and benefits.

Area of Science:

  • Oncology
  • Radiology
  • Preventive Medicine

Background:

  • Randomized controlled trials (RCTs) involving nearly 500,000 women confirm screening mammography's role in reducing breast cancer mortality.
  • Observed benefits of mammographic screening vary across different age groups.
  • The precise mortality reduction for women over 70 remains uncertain.

Purpose of the Study:

  • To evaluate the effectiveness of screening mammography across different age demographics.
  • To analyze disparities in mammographic screening benefits among women.
  • To inform clinical recommendations and public health policy regarding breast cancer screening.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) on screening mammography.
  • Analysis of data from nearly 500,000 women across two continents.

Related Experiment Videos

  • Evaluation of age-specific mortality reduction and screening test characteristics.

    • Main Results:

    • Mammographic screening significantly reduces breast cancer mortality in women aged 50-69.
    • Women aged 40-49 show a lesser benefit compared to older age groups, potentially due to differing tumor biology and mammographic characteristics.
    • Absolute risk reduction is lower in younger women, irrespective of screening technology or interval adjustments.

    Conclusions:

    • Strong support for routine mammographic screening for women aged 50-69 every 2 years.
    • Screening women over 70 with favorable life expectancy is considered reasonable.
    • Evidence does not support a universal recommendation for screening women aged 40-49; individualized physician-patient discussions are advocated pending further research.