Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modelling surface potentials from intracochlear electrical stimulation.

L H Mens1, G Huiskamp, T Oostendorp

  • 1Department of ENT, University Hospital Nijmegen, The Netherlands. l.mens@kno.azn.nl

Scandinavian Audiology
|November 26, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-omics profiling of chronic immune-mediated skin diseases: SKINERGY protocol and strategic evaluation.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

An Overview of the Protein Binding of Cephalosporins in Human Body Fluids: A Systematic Review.

Frontiers in pharmacology·2022
Same author

Experimental study of diclofenac and its biliary metabolites on anastomotic healing.

BJS open·2018
Same author

Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells.

British journal of cancer·2014
Same author

Abstracts of Presentations at the International Conference on Basic and Clinical Multimodal Imaging (BaCI), a Joint Conference of the International Society for Neuroimaging in Psychiatry (ISNIP), the International Society for Functional Source Imaging (ISFSI), the International Society for Bioelectromagnetism (ISBEM), the International Society for Brain Electromagnetic Topography (ISBET), and the EEG and Clinical Neuroscience Society (ECNS), in Geneva, Switzerland, September 5-8, 2013.

Clinical EEG and neuroscience·2013
Same author

Neonatal sepsis in a neonatal intensive care unit in Indonesia.

The Journal of hospital infection·2009
Same journal

Vision and hearing in old age.

Scandinavian audiology·2002
Same journal

Two families with phenotypically different hereditary low frequency hearing impairment: longitudinal data and linkage analysis.

Scandinavian audiology·2002
Same journal

Age and noise-induced hearing loss.

Scandinavian audiology·2002
Same journal

Bilateral hearing aids--effects and consequences from a user perspective.

Scandinavian audiology·2002
Same journal

Threshold-based fitting methods for non-linear (WDRC) hearing instruments--comparison of acoustic characteristics.

Scandinavian audiology·2002
Same journal

Will hearing healthcare be affordable in the new millennium.

Scandinavian audiology·2001
See all related articles

Cochlear implant models reveal high impedance in non-otosclerosis patients, explaining surface potentials. This finding highlights the role of cochlear bone resistivity in auditory signal transmission.

Area of Science:

  • Biomedical Engineering
  • Auditory Neuroscience
  • Medical Imaging

Background:

  • Cochlear implant surgery aims to restore hearing by stimulating the auditory nerve.
  • Understanding electrical potential distribution in the cochlea is crucial for optimizing implant performance.
  • Previous studies have qualitatively modeled surface potentials in cochlear implant patients.

Purpose of the Study:

  • To qualitatively model surface potentials recorded from cochlear implant patients.
  • To investigate the influence of cochlear bone resistivity on surface potential distribution.
  • To differentiate potential generation mechanisms in patients with and without otosclerosis.

Main Methods:

  • Construction of several head volume conduction models with distinct compartments (skin, skull, brain, cochlea, ear canals).

Related Experiment Videos

  • Development of a "petrous bone" model simulating the cochlea as a cavity within a bony layer.
  • Utilizing a high resistivity ratio (1:100) between bony and other compartments in the petrous bone model.

    • Main Results:

    • Models for otosclerosis patients reflected equivalent dipole orientation.
    • Models for non-otosclerosis patients showed potentials increasing with electrode distance, suggesting varying cochlear bone resistivity.
    • The petrous bone model with a high resistivity ratio successfully replicated potentials observed in non-otosclerosis patients.

    Conclusions:

    • Surface potentials in non-otosclerosis patients are explained by high impedance between cochlear turns.
    • Current return pathways via the petrous bone wall into the brain compartment contribute to observed potentials.
    • Cochlear bone's electrical properties significantly influence auditory signal propagation and surface potential measurements.