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Updated: Aug 10, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Coexisting myelodysplasia and myeloproliferative features in a single clone containing 5q-, Ph and i(17q)
C A Garay1, T Al-Saleem, J R Testa
1Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Abstract:
A case with myelodysplasia in which a single clone contained both 5q- and Ph chromosomes at diagnosis is presented. The patient subsequently developed leukocytosis and at that time was found to have acquired an additional chromosomal abnormality, i(17)(q10). This case illustrates the role of three different genetic changes that impart different clinical characteristics, i.e. myelodysplastic as well as myeloproliferative changes, as part of a multistep leukemogenic process.
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