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Development and validation of a questionnaire to measure asthma control
E F Juniper1, P M O'Byrne, G H Guyatt
1Dept of Clinical Epidemiology and Biostatistics, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada.
The European Respiratory Journal
|November 26, 1999
Summary
The Asthma Control Questionnaire (ACQ) was developed and validated to measure asthma control effectively. This reliable tool accurately assesses symptom control and medication use in asthma patients.
Area of Science:
- Pulmonology
- Clinical Medicine
- Health Outcomes Research
Background:
- International asthma management guidelines prioritize optimal asthma control.
- Existing methods for assessing asthma control require refinement for clinical practice.
Purpose of the Study:
- To develop and validate a comprehensive Asthma Control Questionnaire (ACQ).
- To create a reliable and responsive tool for measuring asthma control in clinical settings.
Main Methods:
- Expert consensus from 100 international asthma clinicians identified key symptoms.
- A 7-question survey including symptoms, beta2-agonist use, and airway calibre was developed.
- A 9-week observational study with 50 adult asthma patients assessed ACQ reliability and validity.
Main Results:
- The ACQ demonstrated high reliability (ICC=0.90) in stable asthma patients.
- The questionnaire was highly responsive to changes in asthma control (p<0.0001).
- Correlations supported the cross-sectional and longitudinal validity of the ACQ against other health status measures.
Conclusions:
- The developed Asthma Control Questionnaire possesses strong evaluative and discriminative properties.
- The ACQ is a validated instrument that can be confidently used to measure asthma control.
- This tool supports the goal of achieving optimum asthma control as recommended by international guidelines.