Trichoepithelioma associated with cellular blue nevus
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Updated: Sep 12, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
1Department of Pathology, Vancouver Hospital and Health Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.
Background:
Epithelial elements, such as trichoepithelioma, are occasionally associated with melanocytic nevi.
Objective:
A case of trichoepithelioma in association with cellular blue nevus is reported.
Methods And Results:
A solitary, pigmented nodule was removed from the scalp of a middle-aged woman. Histopathologic examination demonstrated a circumscribed cellular blue nevus within which were embedded epithelial strands and cystic structures consistent with trichoepithelioma.
Conclusion:
Trichoepitheliomas have been described in relation to common acquired nevi, but an association with a blue nevus is rare. The intimate admixture of trichoepithelioma within the nodule of a nevus supports the concept of epithelial induction by melanocytic nevi.
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