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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Jul 18, 2026

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Functional MRI in children with epilepsy.

S Y Bookheimer1, M Dapretto, U Karmarkar

  • 1Division of Brain Mapping, University of California, Los Angeles, CA, USA. sbook@ucla.edu

Developmental Neuroscience
|November 27, 1999
PubMed
Summary

Functional magnetic resonance imaging (fMRI) aids in understanding pediatric brain language organization. Preoperative fMRI in children with epilepsy helps localize language before surgery, reducing risks of new deficits.

Area of Science:

  • Neuroscience
  • Developmental neuroscience
  • Pediatric neurology

Background:

  • Functional magnetic resonance imaging (fMRI) advances brain mapping.
  • Understanding language organization in the developing brain is crucial.
  • Pediatric epilepsy patients may require surgical intervention.

Purpose of the Study:

  • To explore functional magnetic resonance imaging (fMRI) for language mapping in pediatric epilepsy.
  • To assess the impact of epileptic lesions on language organization during cognitive development.
  • To inform clinical applications of fMRI in pediatric pre-surgical planning.

Main Methods:

  • Review of current brain mapping techniques in children.
  • Application of fMRI for language localization in pediatric epilepsy cases.

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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
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Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
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Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy

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  • Analysis of early results from fMRI language mapping.

    • Main Results:

    • fMRI offers insights into language organization in developing brains.
    • Preoperative fMRI can assist in localizing language functions.
    • Early findings suggest fMRI's utility in pediatric epilepsy surgery planning.

    Conclusions:

    • fMRI is a valuable tool for language mapping in pediatric epilepsy.
    • Further research is needed on how lesions affect language development.
    • fMRI can help minimize risks associated with epilepsy surgery.