[The development of non-Hodgkin's lymphoma during the course of autoimmune diseases. Five case reports]

The development of five of non-Hodgkin lymphomas during the course of autoimmune diseases was presented. The treatment methods of autoimmune disease included: irradiation steroids, non-steroidal anti-inflammatory drugs or immuno-suppressive drugs. The time interval between diagnosis of autoimmune disease and lymphoma was from 2 to 28 years. High-grade lymphoma was observed in all cases. After treatment (irradiation with or without combination with multidrug chemotherapy) the complete regression was observed and disease-free survival between 16 and 48 months after treatment was obtained.