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Related Experiment Videos

[The coat color mutation in silver foxes (Vulpes vulpes): morphology of guard hairs].

L A Prasolova1, S Jing

  • 1Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia. oskina@bionet.nsc.ru

Genetika
|November 27, 1999
PubMed
Summary

The mottling mutation in domesticated silver foxes alters guard hair structure, affecting scale patterns and melanocyte presence. These changes impact hair thickness, length, and overall appearance.

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Area of Science:

  • Genetics and Molecular Biology
  • Animal Science
  • Dermatology

Context:

  • Domestication of silver foxes has led to genetic mutations affecting coat color, specifically the mottling mutation.
  • Guard hairs are crucial for animal pelage, providing protection and insulation.

Purpose:

  • To investigate the structural differences in guard hairs between normal and mottled silver foxes.
  • To elucidate the cellular and structural basis of the mottling mutation in silver fox guard hairs.

Summary:

  • Guard hairs from mottled areas exhibit significant structural deviations compared to silvery-black hairs.
  • These distinctions include altered grana-shaft separation, reduced thickness and length, modified scale morphology, and different cortical-medullar layer ratios.
  • Furthermore, mottled hairs show a decreased number of melanocytes in hair bulbs and fewer dendritic processes in melanocytes.

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Impact:

  • Provides insights into the genetic control of coat color and hair morphology in canids.
  • Contributes to understanding the phenotypic consequences of domestication-associated mutations.
  • Offers a basis for further research into the molecular mechanisms of melanogenesis and hair development.