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Acyclic structural variants of growth hormone secretagogue L-692,429
P Lin1, J M Pisano, W R Schoen
1Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.
Bioorganic & Medicinal Chemistry Letters
|November 27, 1999
Abstract:
Systematic investigation of acyclic analogs of L-692,429, the prototype benzolactam growth hormone secretagogue, has helped to further define the structural requirements for the release of growth hormone from rat pituitary cells for this class of secretagogues.