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Further hypotensive metabolites from Verbesina caracasana
G Delle Monache1, A R Volpe, F Delle Monache
1Centro Chimica dei Recettori, Università Cattolica, Rome, Italy. g.dellemonache@uniserv.ccr.rm.cnr.it
Bioorganic & Medicinal Chemistry Letters
|November 27, 1999
Abstract:
After the isolation of caracasanamide and caracasandiamide, further hypotensive components of Verbesina caracasana were shown to be N3-prenylagmatine, N1-3',4'-dimethoxycinnamoylagmatine, agmatine and galegin (prenylguanidine). The structures were assigned on the basis of the spectral data of both metabolites and products from their alkaline hydrolyses. A pharmacological analysis of these products is also presented.