Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Long-term endothelial dysfunction after coronary artery stenting.

P R Caramori1, V C Lima, P H Seidelin

  • 1Bayer Inc., Department of Medicine, Mount Sinai Hospital, University of Toronto, Canada.

Journal of the American College of Cardiology
|November 30, 1999
PubMed
Summary

Long-term stenting causes more severe endothelial dysfunction compared to balloon angioplasty or directional atherectomy. This impaired vasomotor function in coronary arteries may influence future atherosclerosis progression after interventions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Widespread slow growth of acquisitive tree species.

Nature·2025
Same author

Neutron resonance absorption imaging of simulated high-level radioactive waste in borosilicate glass.

Scientific reports·2023
Same author

Anaesthetic machine leak not detected by the universal leak test.

Anaesthesia·2019
Same author

Microbial Flora of Pond-Reared Shrimp ( Penaeus stylirostris , Penaeus vannamei , and Penaeus setiferus ).

Journal of food protection·2019
Same author

Intra-operative failure of sevoflurane vaporiser.

Anaesthesia·2018
Same author

Differential Cross Section and Photon-Beam Asymmetry for the γ[over →]p → π^{-}Δ^{++}(1232) Reaction at Forward π^{-} Angles for E_{γ}=1.5-2.95  GeV.

Physical review letters·2018

Area of Science:

  • Cardiovascular medicine
  • Interventional cardiology
  • Vascular biology

Background:

  • Percutaneous coronary interventions cause arterial injury, potentially leading to chronic endothelial dysfunction.
  • Long-term effects of various percutaneous coronary interventions on endothelial function remain unclear.

Purpose of the Study:

  • To assess endothelial-dependent vasomotor function in nonrestenotic coronary arteries over six months post-stent implantation, balloon angioplasty (BA), and directional atherectomy (DCA).

Main Methods:

  • Evaluated 39 patients with isolated proximal left anterior descending (LAD) stenosis treated >6 months prior without restenosis.
  • Assessed changes in LAD and circumflex (Cx) artery diameter via quantitative angiography during intracoronary acetylcholine infusion.
  • Compared outcomes for patients treated with stenting (12), BA (15), and DCA (12).

Related Experiment Videos

Main Results:

  • Patients with prior stenting showed significantly greater LAD constriction (-21.8%) compared to BA (-9.5%) or DCA (-9.1%) groups (p=0.02).
  • No significant difference in Cx artery constriction was observed across the three groups (p=0.47).
  • Previous stent implantation was the sole significant predictor of LAD constriction (p=0.008).

Conclusions:

  • Long-term endothelial dysfunction is more pronounced after coronary stenting than after BA or DCA.
  • Findings suggest potential implications for atherosclerosis progression in stented coronary arteries.