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Exophiala jeanselmei causing late endophthalmitis after cataract surgery
A L Hofling-Lima1, D Freitas, O Fischman
1Department of Ophthalmology, Federal University of São Paulo, Brazil.
Purpose:
To report two cases of late endophthalmitis caused by Exophiala jeanselmei after cataract surgery.
Methods:
Case reports, including clinical evaluation, direct examination, and culture of the aqueous humor.
Results:
In each case, samples from the anterior chamber had positive growth of yeasts with toruloid hyphae and pseudohyphae. Intravitreal and anterior chamber amphotericin B were used in both cases. Apparent clinical resolution was achieved, but after 3 months in one case and 6 months in the other the infection recurred more aggressively, with severe endophthalmitis leading to ocular atrophy.
Conclusion:
E. jeanselmei causes a severe intraocular infection and isolation, and identification of the agent ensures proper diagnosis and treatment. After clinical resolution of the infection, careful and long-term follow-up is recommended to promptly detect relapse and immediately reintroduce treatment.