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Related Experiment Videos

Optic disk size in open-angle glaucoma: the Blue Mountains Eye Study.

P R Healey1, P Mitchell

  • 1Department of Ophthalmology, the University of Sydney, Westmead, NSW, Australia.

American Journal of Ophthalmology
|November 30, 1999
PubMed
Summary
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Glaucoma patients have slightly larger optic disks than those without the condition. This study compared optic disk size in older adults with and without glaucoma, ocular hypertension, or pseudoexfoliation syndrome.

Area of Science:

  • Ophthalmology
  • Optometry
  • Glaucoma Research

Background:

  • Optic disk size is a key factor in diagnosing glaucoma.
  • Variations in optic disk size can influence glaucoma risk assessment.
  • Understanding optic disk morphology in different ocular conditions is crucial.

Purpose of the Study:

  • To compare optic disk size between normal eyes and eyes with open-angle glaucoma, ocular hypertension, or pseudoexfoliation syndrome.
  • To investigate optic disk dimensions in an older, population-based sample.
  • To determine if optic disk size differs significantly across these ocular health classifications.

Main Methods:

  • Utilized data from the Blue Mountains Eye Study, including 3,654 subjects.
  • Measured vertical disk diameter from stereoscopic disk photographs.

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  • Employed spherical equivalent refraction for magnification correction and analyzed data using a general estimating equation model.

    • Main Results:

    • Mean optic disk diameter was 1.556 mm in glaucomatous eyes.
    • This was significantly larger (P <.05) than in normal eyes (1.506 mm).
    • Eyes with ocular hypertension (1.494 mm) and pseudoexfoliation (1.501 mm) also showed smaller mean disk diameters compared to glaucomatous eyes.

    Conclusions:

    • Individuals with glaucoma exhibit slightly larger optic disks compared to non-glaucomatous subjects.
    • Optic disk size may serve as a distinguishing feature in glaucoma diagnosis.
    • Further research into optic disk morphology and its relation to glaucoma progression is warranted.