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Endometrial polyps during menopause: characterization and significance.
R Orvieto1, I Bar-Hava, D Dicker
1Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tiqva, Israel.
Acta Obstetricia Et Gynecologica Scandinavica
|November 30, 1999
Summary
Postmenopausal endometrial polyps are common and usually benign. However, hormone replacement therapy users show a higher risk of endometrial hyperplasia, necessitating thorough histological evaluation.
Area of Science:
- Gynecology
- Reproductive Medicine
- Pathology
Background:
- Endometrial polyps are common in postmenopausal women.
- Characterizing these polyps is crucial for understanding their clinical significance.
Purpose of the Study:
- To characterize postmenopausal women diagnosed with endometrial polyps.
- To evaluate the significance of endometrial polyps in this demographic.
Main Methods:
- Retrospective analysis of consecutive postmenopausal patients with endometrial polyps over a two-year period.
- Assessment of demographic, medical, and gynecological data correlated with histological findings.
Main Results:
- Of 146 patients, 15 had endometrial hyperplasia (4 with atypia); no endometrial carcinoma was found.
- Hormone replacement therapy (HRT) users (13.7%) had a significantly higher rate of endometrial hyperplasia compared to non-users (p<0.006).
- No significant differences in presenting symptoms, signs, ultrasonographic findings, or medical histories were observed across histological categories.
Conclusions:
- Postmenopausal endometrial polyps are generally benign but require thorough histological evaluation.
- A higher incidence of endometrial hyperplasia is noted in HRT users with endometrial polyps.
- This highlights the importance of histological assessment, particularly in HRT users, to rule out hyperplasia.