Related Experiment Video
Updated: Aug 18, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Relationship between passive smoking, recurrent respiratory tract infections and otitis media in children
D Gryczyńska1, J Kobos, A Zakrzewska
1Department of Pediatric Otolaryngology, University Medical School of Lodz, Institute of Pediatrics, Poland.
Insights
Passive smoking and daycare are key risks for recurrent upper respiratory tract infections (URTI) in children. Exposure to cigarette smoke significantly alters adenoid tissue, impacting children
Area of Science:
- Otolaryngology
- Pediatrics
- Environmental Health
Background:
- Upper respiratory tract infections (URTI) and otitis media are common in children.
- Multifactorial causes include enlarged adenoids, environmental factors, daycare, smoking parents, and allergies.
- Viral infections damage nasopharyngeal ciliary cells and mucociliary clearance, leading to Eustachian tube dysfunction and otitis media.
Purpose of the Study:
- To evaluate factors contributing to recurrent URTI and otitis media in children.
- To conduct clinical and histopathological examinations of adenoid tissue in children exposed and unexposed to passive smoking.
- To assess differences in ciliary-mucous transport between passive smokers and non-exposed children.
Main Methods:
- Analysis of interview questionnaires from 1000 children aged 3-14 years.
- Histopathological examination of adenoid tissue from children with recurrent URTI and otitis media, comparing those exposed and unexposed to cigarette smoke.
Main Results:
- Socio-economic conditions, daycare attendance, and passive smoking are significant risk factors for URTI.
- Allergies were present in 35-38% of children with URTI.
- Histopathological and ultrastructural evaluations revealed significant differences in adenoid tissue between passive smoking children and those not exposed to smoke.
Conclusions:
- Passive smoking is a critical risk factor for recurrent URTI and otitis media in children.
- Adenoid tissue in children exposed to passive smoke shows distinct pathological changes.
- Understanding these factors can inform preventative strategies and treatment for pediatric URTI and otitis media.
Unlabelled:
The cause of upper respiratory tract infections (URTI) are multifactorial (enlarged adenoid, environmental conditions, staying at the care centers, smoking parents, allergy). Directly, viral infection causes damage to the ciliary cells and mucociliary clearance in the nasopharynx and Eustachian tube, promotes tubal occlusion and provokes otitis media. Enlarged adenoids reduce ventilation to the nasopharynx, increase accumulation of the secretion and provide a good condition for bacteria.
Aims Of The Study:
Evaluation of the factors playing a role in recurrent URTI and otitis media in children. Clinical and histopathological examination of adenoid tissue of children who were passive smokers and children who were not exposed to cigarette smoke. Evaluation of the difference between ciliary-mucous transport among passive smokers and children not exposed to cigarette smoke.
Methods:
The analysis of interview questionnaires in 1000 children aged 3-14 years. Histopathological examinations of adenoid tissue excised in the group of children of recurrent upper respiratory tract infections and serous otitis media exposed and not exposed to cigarette smoke.
Conclusions:
Among the risk factors for URTI, the most important are: (1) socio-economic conditions; (2) staying at day care centers; and (3) passive smoking. Allergy was confirmed in 35-38% of URTI children. Surgical treatment was undertaken in 11.4-32.5% of URTI children (tonsilloadenoidectomy). Histopathological and ultrastructural evaluation of adenoid tissue in passive smoking children indicates significant differences to children not exposed to cigarette smoke.
Related Concept Videos
Physical Assessment of the Respiratory Tract I: Health History
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and key...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Microbiota of the Respiratory Tract
Asthma I: Introduction
Chronic Obstructive Pulmonary Disease I: Introduction
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

