DAP kinase and DAP-3: novel positive mediators of apoptosis

Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation.

Journal of internal medicine·2017

DAPK2 is a novel regulator of mTORC1 activity and autophagy.

Cell death and differentiation·2014

Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.

Cell death & disease·2014

The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA.

Oncogene·2013

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk.

Cell death and differentiation·2011

Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.

Oncogene·2011

Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design.

Annals of the rheumatic diseases·2026

Sequential disease activity assessment for predicting future treatment trajectories in patients with rheumatoid arthritis treated with JAK inhibitors: a group-based trajectory and landmark analysis.

Annals of the rheumatic diseases·2026

A new humanised TCR transgenic mouse model to study T cells reactive to citrullinated tenascin C, a relevant autoantigen in rheumatoid arthritis.

Annals of the rheumatic diseases·2026

Automated detection of active and structural MRI lesions in the sacroiliac joints in axial spondyloarthritis: training and validation across 3 phase III clinical trial datasets.

Annals of the rheumatic diseases·2026

Performance of a triage approach for identification of patients with inflammatory rheumatic and musculoskeletal diseases among rheumatology referrals.

Annals of the rheumatic diseases·2026

Validation of systemic Juvenile Arthritis Disease Activity Score 10 in adults with Still's disease.

Annals of the rheumatic diseases·2026

Onvansertib-mediated PLK1 inhibition impairs spermatogenesis in the murine testis.

Asian journal of andrology·2026

RHOA Deletion Downregulates CD19 and Promotes Dysfunctional Immune Microenvironments in CAR-T Resistant Large B-cell Lymphomas.

Blood cancer discovery·2026

BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Approach for Castration and Enzalutamide Resistant Prostate Cancer.

Cancer research·2026

Emerging therapeutic strategies and clinical development of investigational agents for conventional chondrosarcoma.

Expert opinion on investigational drugs·2026

MH-Penile-002: a phase II, prospective, single-arm trial of neoadjuvant anti-EGFR antibody-drug conjugate plus PD-1 inhibitor in penile cancer with challenging penile preservation or regional lymph node metastasis.

Future oncology (London, England)·2026

Real-world treatment patterns in men with metastatic hormone-sensitive prostate cancer in Europe and Asia between 2020 and 2024.

The oncologist·2026

Related Experiment Videos

DAP kinase and DAP-3: novel positive mediators of apoptosis

Related Concept Videos

Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation.

DAPK2 is a novel regulator of mTORC1 activity and autophagy.

Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.

The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA.

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk.

Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.

Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design.

Sequential disease activity assessment for predicting future treatment trajectories in patients with rheumatoid arthritis treated with JAK inhibitors: a group-based trajectory and landmark analysis.

A new humanised TCR transgenic mouse model to study T cells reactive to citrullinated tenascin C, a relevant autoantigen in rheumatoid arthritis.

Automated detection of active and structural MRI lesions in the sacroiliac joints in axial spondyloarthritis: training and validation across 3 phase III clinical trial datasets.

Performance of a triage approach for identification of patients with inflammatory rheumatic and musculoskeletal diseases among rheumatology referrals.

Validation of systemic Juvenile Arthritis Disease Activity Score 10 in adults with Still's disease.

Onvansertib-mediated PLK1 inhibition impairs spermatogenesis in the murine testis.

RHOA Deletion Downregulates CD19 and Promotes Dysfunctional Immune Microenvironments in CAR-T Resistant Large B-cell Lymphomas.

BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Approach for Castration and Enzalutamide Resistant Prostate Cancer.

Emerging therapeutic strategies and clinical development of investigational agents for conventional chondrosarcoma.

MH-Penile-002: a phase II, prospective, single-arm trial of neoadjuvant anti-EGFR antibody-drug conjugate plus PD-1 inhibitor in penile cancer with challenging penile preservation or regional lymph node metastasis.

Real-world treatment patterns in men with metastatic hormone-sensitive prostate cancer in Europe and Asia between 2020 and 2024.

Related Experiment Videos

DAP kinase and DAP-3: novel positive mediators of apoptosis

Related Concept Videos

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