[Electrophoretic study of serum proteins in patients with periodontal diseases]

Electrophoretic study of the serum proteins in individuals with periodontal disease. Total protein was determined in serum samples from 20 subjects affected with periodontal disease and from 20 healthy persons. In addition the authors performed paper chromatographic and immuno-electrophoretic studies. It was found that the relative ans also the absolute mean values for gamma globulins were significantly higher in the control group. In individuals affected with periodontal disease, an increase of all three immunoglobulins (i.e., IgA, IgG and IgM) was observed in 10 of 20 cases, whereas such an increase occurred but once in the control group. The increase in the immunoglobulin content of serum samples from individuals affected with periodontal disease is brought in relation to the inflammatory condition of the periodontium.