Related Experiment Video
Updated: Oct 18, 2026

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Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
Published on: June 29, 2022
Immunomodulatory effects of vitamin D analog KH1060 on an experimental skin transplantation model
D L Bertolini1, P R Araújo, R N Silva
1Lab of Allergy and Immunology, School of Medicine, University of São Paulo, Brazil.
Transplantation Proceedings
|December 1, 1999
Abstract
No abstract available in PubMed .
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Cell-mediated Immune Responses
Overview

