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Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
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Posttranslational processing of progrowth hormone-releasing hormone

E A Nillni1, R Steinmetz, O H Pescovitz

  • 1Department of Medicine, Brown University School of Medicine, Rhode Island Hospital, Providence 02903, USA.

Endocrinology
|December 1, 1999
PubMed
Summary

The study reveals new insights into how prepro-GH-releasing hormone (prepro-GHRH) is processed, identifying novel peptides beyond GHRH. These peptides, including GHRH-related peptide (GHRH-RP), show potential biological activity by stimulating the PKA pathway.

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