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Dihydrochalcones and flavonolignans from Iryanthera lancifolia
D H Silva1, S C Davino, S B Barros
1Instituto de Qu¿imica, Universidade de Såo Paulo, C.P. 26077, CEP 05599-970, Såo Paulo-SP, Brazil, Instituto de Qu¿imica, Universidade Estadual Paulista, C.P. 355, CEP 14800-900, Araraquara-SP, Brazil, and Faculdade de Ci¿enc. dhsilva@iq.unesp.br
Abstract:
An extract from the pericarps of I. lancifolia afforded two dihydrochalcones (1 and 2) and two flavonolignans (3 and 4), with compounds 2-4 being of novel structure. The antioxidant activities of compounds 1-4 were evaluated through the measurement of malondialdehyde production, and Q(1/2) (concentration necessary for 50% inhibition of autoxidation) data were calculated. The Q(1/2) values obtained for 1-4 and the standard compounds alpha-tocopherol and quercetin were 6.9, 4.7, 5.5, 4.8, 12.1, and 7.6 microg/mL, respectively.