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Novel highly oxygenated bisabolane sesquiterpenes from Cremanthodium discoideum
1Department of Chemistry, National Laboratory of Applied Organic Chemistry, Chemistry and Chemical Engineering College, Lanzhou University, Lanzhou 730000, People's Republic of China.
Journal of Natural Products
|December 2, 1999
Abstract:
Five new highly oxygenated bisabolane sesquiterpenes (1-5) were isolated from Cremanthodium discoideum. Their structures were elucidated on the basis of spectroscopic analysis and chemical transformations. The structure and relative stereochemistry of 1 were determined by single-crystal X-ray crystallography on the acetate derivative, 1a. Compound 1 showed antibacterial activity against Bacillus acidilatici and Bacillus subtilis.