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Updated: Aug 3, 2026
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Limonoids from Swietenia macrophylla and S. aubrevilleana
1Departments of Chemistry and Plant Sciences, University of the West Indies, St. Augustine, Trinidad and Tobago, and Department of Chemistry, University of Toronto, Ontario, Canada. bmoot@tstt.net.tt
Abstract:
An investigation of the seeds of Swietenia macrophylla and S. aubrevilleana (Meliaceae) is reported. Three new compounds, augustineolide (1) and 3beta,6-dihydroxydihydrocarapin (2) from S. macrophylla and 6-acetoxyhumilinolide C (3) from S. aubrevilleana were isolated and characterized along with fifteen known compounds. Four of the compounds were subjected to an antifeedant bioassay on the final instar larvae of Spodoptera frugiperda. The antifeedant activity was comparable to that of bicyclononanolides previously tested.
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