Effect of chlorhexidine on dental plaque formation under periodontal pack

In a first experiment, no appreciable differences in plaque formation under periodontal packs were observed in subjects rinsing with and without 0.2% chlorhexidine digluconate. In a second experiment, one gram periodontal packs were coated with 15 to 20 mg of chlorhexidine dihydrochloride powder prior to application and allowed to remain in situ for 4 days. Significantly less plaque formed under periodontal packs with chlorhexidine powder than with control packs. Chlorhexidine dihydrochloride powder may be recommended under periodontal packs for reduction of microbial plaque.