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[Extracellular matrix components in ovarian tumors]
M Wolańska1, K Sobolewski, M Drozdzewicz
1Zakładu Biochemii Akademii Medycznej w Białymstoku.
Ginekologia Polska
|December 3, 1999
Abstract:
This report describes the collagen, glycosaminoglycans and elastin--composition of ovarian tumours. Rearrangement of extracellular matrix in ovarian tumour has been found. There was an increase of total collagen content in comparison to control. Type I collagen was found to be predominant in both tissues. Both tissues, normal and neoplastic one, contain all known glycosaminoglycans. Among them dermatan sulphate was found to be the most abundant. In ovarian tumour an increase of this glycosaminoglycan content was observed.