[Genetics of male sterility]

Infertility affects 10 to 15% of all couples, the man responsible being in approximately half of the cases. With the development of assisted reproductive technologies such as ICSI (Intracytoplasmic Sperm Injection), some infertile men can reproduce and transmit the infertility to their offspring. The genetic basis of male infertility has been extensively studied these last years. This article gives a non exhaustive overview of genetic defects associated with infertility, and emphasizes the importance of genetic screening, and possibly genetic counseling for these infertile males.