Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chlamydia trachomatis: impact on human reproduction.

J Paavonen1, W Eggert-Kruse

  • 1Department of Obstetrics and Gynecology, University of Helsinki, Finland. jorma.paavonen@huch.fi

Human Reproduction Update
|December 3, 1999
PubMed
Summary

Chlamydia trachomatis is a widespread bacterial sexually transmitted infection (STI) causing significant reproductive health issues, particularly in women. Early detection through screening is crucial for preventing long-term complications like infertility.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human papillomavirus vaccine efficacy against invasive, HPV-positive cancers: population-based follow-up of a cluster-randomised trial.

BMJ open·2022
Same author

Erratum for Hokynar et al., "Molecular Evidence of <i>Chlamydia</i>-Like Organisms in the Feces of <i>Myotis daubentonii</i> Bats".

Applied and environmental microbiology·2019
Same author

Serum antibody response to Chlamydia trachomatis TroA and HtrA in women with tubal factor infertility.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2018
Same author

Molecular Evidence of Chlamydia-Like Organisms in the Feces of Myotis daubentonii Bats.

Applied and environmental microbiology·2016
Same author

Antibody to Chlamydia trachomatis proteins, TroA and HtrA, as a biomarker for Chlamydia trachomatis infection.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2016
Same author

Comparison of amniotic fluid matrix metalloproteinase-8 and cathelicidin in the diagnosis of intra-amniotic infection.

Journal of perinatology : official journal of the California Perinatal Association·2016

Area of Science:

  • Reproductive Health
  • Infectious Diseases
  • Public Health

Background:

  • Chlamydia trachomatis is the most common bacterial STI globally, leading to substantial morbidity.
  • Sequelae include pelvic inflammatory disease (PID), ectopic pregnancy, infertility, and reactive arthritis, with PID being a major preventable cause of infertility.
  • While primarily impacting women's reproductive health, research on male infertility links is limited.

Purpose of the Study:

  • To highlight the global burden of Chlamydia trachomatis infections.
  • To emphasize the importance of screening for early detection and prevention of sequelae.
  • To discuss current treatment efficacy and the need for improved control strategies.

Main Methods:

  • Review of existing evidence on Chlamydia trachomatis prevalence, morbidity, and sequelae.

Related Experiment Videos

  • Discussion of current treatment regimens (azithromycin, doxycycline) and their efficacy.
  • Evaluation of screening program prerequisites and the impact of nucleic acid amplification tests (NAATs).

    • Main Results:

    • Chlamydial infections are highly prevalent, often asymptomatic, and linked to significant reproductive health complications.
    • Current screening strategies relying on symptomatic patients have been unsuccessful.
    • NAATs offer a sensitive and specific diagnostic tool for population-based screening.

    Conclusions:

    • Screening for Chlamydia trachomatis is essential for preventing long-term reproductive health consequences.
    • The cost-effectiveness of screening outweighs the healthcare costs of treating complications.
    • Further development of population-based screening programs is necessary for effective control.