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Distribution of beta-lactamases in actinomycetes
H Ogawara1, N Kawamura, T Kudo
1Department of Biochemistry, Meiji Pharmaceutical University, Tokyo 204-8588, Japan. hogawara@my-pharm.ac.jp
Antimicrobial Agents and Chemotherapy
|December 3, 1999
Abstract:
The distribution of beta-lactamase activities in a collection of actinomycete strains was surveyed. Six of 127 strains were found to produce beta-lactamase. This low frequency was in contrast to the case with Streptomyces species. The producing strains were not related phylogenetically. MICs of benzylpenicillin did not correlate with beta-lactamase production.