A correlation between microscopic numerical evaluation, clinical scoring and total collagen content in inflamed...

The histopathological observation was carried out on 12 periodontally involved gingivae and the microscopic inflammatory index was utilized for a quantitative expression of the periodontal pathology. Namely, each of 40 to 50 sections obtained from one gingival biospy was microscopically examined concerning the changes in the epithelium of the periodontal pocket and the gingival lamina propria which were divided into several items tested. The total number of the indices for each item examined was defined as the microscopic inflammatory index in individual cases. This index showed a tendency to increase proportionally to the decrease of the amount of collagen per wet weight of gingiva adjacent to the gingival biopsy aforementioned. In evaluating periodontal diseases, this estimation appears to be more objective and reproducible compared with other various indices based on clinical observation.