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Hospital days in risperidone-treated patients.

R A Dickson1, J T Dalby, D Addington

  • 1University of Calgary, Alberta. ruth.dickson@crha-health.ab.ca

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|December 10, 1999
PubMed
Summary

Continuing risperidone treatment significantly reduced inpatient hospital days for schizophrenia-spectrum patients. Those who maintained risperidone therapy experienced fewer hospitalizations compared to those who discontinued the medication.

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Area of Science:

  • Psychiatry
  • Pharmacology
  • Health Services Research

Background:

  • Schizophrenia-spectrum disorders are associated with significant healthcare utilization.
  • Risperidone is a widely used antipsychotic medication for managing these conditions.
  • Understanding real-world treatment outcomes is crucial for optimizing patient care.

Purpose of the Study:

  • To compare inpatient hospital days in schizophrenia-spectrum patients before and after initiating risperidone.
  • To evaluate the impact of risperidone adherence on hospitalization rates.

Main Methods:

  • Retrospective cohort study with a mirror-image design.
  • Involved 120 patients over a 6-year period, analyzing hospital days 3 years pre- and post-risperidone initiation.
  • Data collected via chart review and database extraction from outpatient treatment sites.

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Main Results:

  • Patients were divided into three groups based on risperidone use: continuous (N=35), interrupted/resumed (N=8), and discontinued (N=77).
  • The continuous risperidone group showed a significant decrease in hospital days post-treatment.
  • Overall reduction in inpatient days for the total sample was not statistically significant.

Conclusions:

  • Approximately 29% of patients who consistently used risperidone demonstrated a significant reduction in inpatient hospital days.
  • Average annual hospital days decreased from 17.2 pre-treatment to 2.1 during 3 years of risperidone treatment.
  • Sustained risperidone use appears beneficial in reducing hospitalizations for select schizophrenia-spectrum patients.