Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Typhoid hepatitis in children.

A K Shetty1, S R Mital, A H Bahrainwala

  • 1Department of Pediatrics, Louisiana State University Medical Centre, New Orleans, USA.

Journal of Tropical Pediatrics
|December 10, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of Concern "Acute exposure to sarin increases blood brain barrier permeability and induces neuropathological changes in the rat brain: Dose-response relationships" [Neurosci. 113(3) (2002) 721-741].

Neuroscience·2024
Same author

Steroid-dependent Kimura Disease in a Child Treated with Cetirizine and Montelukast.

Indian pediatrics·2020
Same author

Curcumin treatment leads to better cognitive and mood function in a model of Gulf War Illness with enhanced neurogenesis, and alleviation of inflammation and mitochondrial dysfunction in the hippocampus.

Brain, behavior, and immunity·2018
Same author

Inborn errors of metabolism (IEM) - an Indian perspective.

Indian journal of pediatrics·2017
Same author

Leigh's subacute nectrotizing encephalomyelopathy: Possible diagnosis by C.T. Scan.

Indian journal of pediatrics·2017
Same author

Learning difficulty and pachydermoperiostosis.

Journal of postgraduate medicine·2014
Same journal

Evaluation of urinary homocysteine levels in children with idiopathic nephrotic syndrome.

Journal of tropical pediatrics·2026
Same journal

Efficacy of Bacillus clausii as an adjuvant therapy in pathological neonatal unconjugated hyperbilirubinemia in the Nile Delta region of Egypt: a randomized controlled trial.

Journal of tropical pediatrics·2026
Same journal

Superior mesenteric artery Doppler after first feed and its association with feed intolerance and necrotizing enterocolitis in very low birth weight neonates: a prospective cohort study.

Journal of tropical pediatrics·2026
Same journal

Moving the needle towards evidence-based guideline development in resource-constrained settings.

Journal of tropical pediatrics·2026
Same journal

Outcome of periviable neonates after implementation of the Tiny Baby Protocol: a prospective study from India.

Journal of tropical pediatrics·2026
Same journal

Role of hematological parameters including systemic immune-inflammation index and percentage of immature granulocytes in predicting acute pyelonephritis.

Journal of tropical pediatrics·2026
See all related articles

Typhoid hepatitis, a rare cause of jaundice in children, presents with fever and liver dysfunction. Prompt antibiotic treatment ensures full recovery, highlighting its importance in tropical differential diagnoses.

Area of Science:

  • Pediatrics
  • Hepatology
  • Infectious Diseases

Background:

  • Liver involvement is common in typhoid fever, but a hepatitis-like presentation is rare in children.
  • Typhoid hepatitis can mimic acute viral hepatitis, posing diagnostic challenges.

Purpose of the Study:

  • To characterize the clinical presentation, biochemical findings, and prognosis of typhoid hepatitis in pediatric patients.
  • To emphasize the inclusion of typhoid hepatitis in the differential diagnosis for febrile, jaundiced children in tropical regions.

Main Methods:

  • A retrospective study of 100 pediatric typhoid fever cases (age 0-12 years) with positive blood cultures for Salmonella typhi.
  • Special focus on identifying and analyzing cases with hepatic dysfunction.

Related Experiment Videos

Main Results:

  • Eight patients (8%) presented with typhoid hepatitis, characterized by high fever, tender hepatomegaly, elevated serum bilirubin (2.5-5.8 mg/dl), and elevated ALT (100-620 IU/l).
  • All eight patients achieved complete clinical and biochemical recovery with appropriate antibiotic therapy.

Conclusions:

  • Typhoid hepatitis is an uncommon but significant manifestation of typhoid fever in children.
  • The clinical presentation of typhoid hepatitis warrants its consideration in the differential diagnosis of acute hepatitis in children, especially in endemic areas.