Related Experiment Videos
Nonlinear analysis of biomagnetic signals recorded from the umbilical artery in normal and pre-eclamptic pregnancies
P A Anninos1, P Anastasiadis, A Kotini
1Laboratory of Medical Physics, Medical School, Democrition University of Thrace, Alexandroupolis, Greece. aninnos@demokritos.cc.duth.gr
Objective:
In this study we investigated the hemodynamics of the feto-placental circulation in normal and pre-eclamptic near term pregnancies using the biomagnetometer SQUID. Thirteen abnormal and 25 normal pregnancies were included in this study.
Study Design:
The biomagnetic signals were analyzed using nonlinear analysis in order to differentiate these two types of pregnancies.
Results:
The application of nonlinear analysis reveal a clear saturation dimension value for pre-eclamptic and non-saturation for normal pregnancies. These findings were statistically significant and were correlated with fetal heart rate monitoring, pH and Apgar score: high biomagnetic cases (140-300 fT/square root Hz) were related with normal patterns, pH>7.25 and Apgar >7, while low biomagnetic recordings (50-110 fT/square root Hz) were connected with abnormal patterns, pH<7.25 and Apgar <7.
Conclusions:
It is suggested that the biomagnetic measurements with SQUID and the application of nonlinear analysis, is a promising procedure in assessing fetal health, especially in high risk pregnancies.