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Neural stem cells in the adult human brain
C B Johansson1, M Svensson, L Wallstedt
1Department of Clinical Neuroscience, Karolinska Institute, Stockholm, SE-171 77, Sweden.
Experimental Cell Research
|December 10, 1999
Abstract:
New neurons are continuously generated in certain regions of the adult brain. Studies in rodents have shown that new neurons are generated from self-renewing multipotent neural stem cells. Here we demonstrate that both the lateral ventricle wall and the hippocampus of the adult human brain harbor self-renewing cells capable of generating neurons, astrocytes, and oligodendrocytes in vitro, i.e., bona fide neural stem cells.