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Updated: Aug 14, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

[Enterovirus infections in children under three months of age]

H Patural1, G Teyssier, B Pozzeto

  • 1Service de réanimation pédiatrique et néonatologie, CHU de Saint-Etienne, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|December 10, 1999
PubMed

Insights

Enterovirus infections in children are usually mild but can cause severe issues in infants and newborns. Current treatments are limited, with research exploring immunoglobulins, immunization, and anti-proteases.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Neonatal Medicine

Context:

  • Enterovirus infections, including echoviruses and coxsackie viruses, are common in childhood.
  • While often benign, these infections pose significant risks in infants and neonates, potentially causing severe neurological or cardiac complications.
  • Distinguishing enterovirus infections from bacterial infections in neonates is clinically challenging.

Purpose:

  • To review the clinical presentation, diagnosis, and potential therapeutic strategies for enterovirus infections in pediatric populations.
  • To highlight the specific risks and diagnostic difficulties associated with enteroviruses in neonates.
  • To discuss emerging therapeutic avenues for enterovirus infections.

Summary:

  • Enterovirus infections in children present with diverse, non-specific symptoms, generally benign except for poliovirus.
  • Severe neurological and cardiac lesions can occur in infants, and neonatal infections mimic bacterial sepsis, with maternal transmission posing risks.
  • Diagnosis relies on viral cultures and PCR; effective antiviral drugs are lacking, but intravenous immunoglobulins, immunization, and anti-proteases are under investigation.

Impact:

  • Informing clinicians about the varied clinical spectrum of enterovirus infections in children.
  • Improving diagnostic approaches and early recognition of severe cases in infants and neonates.
  • Guiding future research and development of effective treatments for enterovirus infections.

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