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Updated: Oct 18, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
Neurothekeoma palpebrae: a rare nerve sheath tumor arising in the eyelid
T T You1, P K Kaiser, T P Netland
1Pacific ClearVision Institute, Eugene, Oregon, USA.
Purpose:
To report a case of an eyelid neurothekeoma, a rare peripheral nerve sheath tumor.
Methods:
Case report.
Results:
An excisional biopsy, performed on a lesion removed from the upper eyelid of a 76-year-old woman, revealed the clinical and histopathologic features of a neurothekeoma, a tumor consisting of multiple collections of spindle cells in a myxomatous background. Immunohistochemical characterization showed positivity for NK1/C3, neuron-specific enolase, and alcian blue.
Conclusion:
Neurothekeoma palpebrae should be considered in the differential diagnosis of solitary nodules of the eyelids.
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