Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Thyroid disorders and dyslipidemias].

M Deschampheleire1, F H Luyckx, A J Scheen

  • 1Département de Biologie clinique, Université de Liège.

Revue Medicale De Liege
|December 10, 1999
PubMed
Summary

Thyroid disturbances, both overt and subclinical, impact lipid profiles. Subclinical hypothyroidism is linked to higher LDL cholesterol, which improves with thyroxine treatment, aiding clinical management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Sitagliptine (Januvia): incretin enhancer potentiating insulin secretion for the treatment of type 2 diabetes].

Revue medicale de Liege·2008
Same author

[Medication of the month. Rimonabant (Acomplia): first CB1 receptor antagonist of the endocannabinoid system].

Revue medicale de Liege·2008
Same author

[Isolated tricuspid valve endocarditis as a cause of fever of unknown origin].

Revue medicale de Liege·2008
Same author

[A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge].

Revue medicale de Liege·2008
Same author

[Therapy of type 2 diabetes: between insulin sensitizers and insulin secreting agents].

Revue medicale de Liege·2008
Same author

[Aspirin resistance in diabetic patients: laboratory entity or clinical reality?].

Revue medicale de Liege·2007

Area of Science:

  • Endocrinology
  • Lipidology
  • Internal Medicine

Context:

  • Overt thyroid dysfunction significantly alters lipid profiles, with normalization upon treatment.
  • Subclinical thyroid dysfunction's impact on lipids, particularly LDL cholesterol, is less understood but increasingly recognized.

Purpose:

  • To review the association between thyroid disturbances (overt and subclinical) and lipid abnormalities.
  • To explore the effects of treating thyroid dysfunction on lipid profiles.
  • To propose clinical management strategies for patients with concurrent thyroid and lipid disorders.

Summary:

  • Severe hyperthyroidism decreases total and LDL cholesterol, while profound hypothyroidism elevates them; treatment normalizes these levels.
  • Subclinical hypothyroidism is associated with elevated LDL cholesterol, which decreases with thyroxine therapy.
  • Meta-analyses suggest a higher prevalence of subclinical hypothyroidism in hypercholesterolemic individuals.

Impact:

  • Provides a comprehensive overview of thyroid-lipid interactions for clinicians.
  • Highlights the importance of assessing thyroid function in patients with dyslipidemia.
  • Informs evidence-based strategies for managing patients with combined thyroid and lipid disorders.

Related Experiment Videos