Identification of DNaseI hypersensitive sites within nuclei

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.

Nature communications·2023

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Leukemia·2012

Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5.

Oncogene·2010

A NF-kappa B/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene.

Journal of immunology (Baltimore, Md. : 1950)·2001

Reconstitution of T cell-specific transcription directed by composite NFAT/Oct elements.

Journal of immunology (Baltimore, Md. : 1950)·2000

Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication.

Plasmid·2000

Integrating AI-Based Protein Modeling and Fragment Molecular Orbital Analysis for Structure-Based Drug Design.

Methods in molecular biology (Clifton, N.J.)·2026

Fragment Molecular Orbital Drug Design Consortium (FMODD): Bridging Academia and Industry Through Prospective FMO-Driven Drug Design.

Methods in molecular biology (Clifton, N.J.)·2026

How Can QM Methods Be Used to Guide Synthesis Planning in Drug Discovery?

Methods in molecular biology (Clifton, N.J.)·2026

Fragment Molecular Orbital-Based Molecular Dynamics (FMO-MD): Current Status and Challenges.

Methods in molecular biology (Clifton, N.J.)·2026

HessFit: Deriving Molecule-Specific Force Fields from Quantum Mechanical Hessians.

Methods in molecular biology (Clifton, N.J.)·2026

Integration of GPCR Modeling with QM for Drug Design: Academic and Industry Collaboration.

Methods in molecular biology (Clifton, N.J.)·2026

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat.

Journal of clinical laboratory analysis·2026

HIPK4 is a novel gene associated with teratozoospermia and male infertility.

Human reproduction open·2026

Edge Preserved U-Net for chromosome edge detection.

Computational biology and chemistry·2026

A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.

International journal of molecular sciences·2026

Circadian Disruption Is Associated with Elevated Whole-Semen mtDNA Copy Number and Implicates CRY1 as a Candidate Regulator in Humans and Mice.

International journal of molecular sciences·2026

A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease.

Cell metabolism·2026

Related Experiment Videos

Identification of DNaseI hypersensitive sites within nuclei

Related Concept Videos

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5.

A NF-kappa B/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene.

Reconstitution of T cell-specific transcription directed by composite NFAT/Oct elements.

Generation of an improved luciferase reporter gene plasmid that employs a novel mechanism for high-copy replication.

Integrating AI-Based Protein Modeling and Fragment Molecular Orbital Analysis for Structure-Based Drug Design.

Fragment Molecular Orbital Drug Design Consortium (FMODD): Bridging Academia and Industry Through Prospective FMO-Driven Drug Design.

How Can QM Methods Be Used to Guide Synthesis Planning in Drug Discovery?

Fragment Molecular Orbital-Based Molecular Dynamics (FMO-MD): Current Status and Challenges.

HessFit: Deriving Molecule-Specific Force Fields from Quantum Mechanical Hessians.

Integration of GPCR Modeling with QM for Drug Design: Academic and Industry Collaboration.

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat.

HIPK4 is a novel gene associated with teratozoospermia and male infertility.

Edge Preserved U-Net for chromosome edge detection.

A Novel SLC25A4 Variant Causing Mitochondrial Dysfunction, Myopathy and Cardiomyopathy: A Functional and Molecular Characterization.

Circadian Disruption Is Associated with Elevated Whole-Semen mtDNA Copy Number and Implicates CRY1 as a Candidate Regulator in Humans and Mice.

A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease.

Related Experiment Videos

Identification of DNaseI hypersensitive sites within nuclei

Related Concept Videos

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