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Related Experiment Videos

Renal pharmacology.

E Jose-Cunilleras1, K W Hinchcliff

  • 1Department of Veterinary Clinical Sciences, Ohio State University, Columbus, USA.

The Veterinary Clinics of North America. Equine Practice
|December 10, 1999
PubMed
Summary
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Pharmacologic treatments for equine urinary tract diseases are limited. This review covers antibiotics for urinary tract infections (UTIs), pH modifiers, smooth muscle drugs, and acute renal failure therapies.

Area of Science:

  • Veterinary Pharmacology
  • Equine Medicine
  • Urology

Background:

  • Pharmacologic interventions for equine urinary tract diseases are restricted.
  • Current treatments include antibiotics, urine pH modifiers, and drugs affecting bladder/urethral function.
  • Management of acute renal failure in horses also involves specific pharmacologic approaches.

Purpose of the Study:

  • To review the available pharmacologic treatments for equine urinary tract diseases.
  • To discuss indications, mechanisms, pharmacokinetics, and adverse effects of these drugs.
  • To contextualize drug use within the pathophysiology of equine urinary conditions.

Main Methods:

  • Literature review of pharmacologic agents used in equine urinary tract disease.
  • Analysis of drug classes including antibiotics, pH modifiers, and smooth muscle agents.

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  • Discussion of treatment strategies for acute renal failure.

    • Main Results:

    • Limited pharmacologic options exist for equine urinary tract conditions.
    • Key drug classes and their applications in urinary tract infections (UTIs) and other disorders are detailed.
    • Information on drug pharmacokinetics and adverse effects is presented.

    Conclusions:

    • Understanding drug mechanisms and pathophysiology is crucial for effective equine urinary tract treatment.
    • The review provides a comprehensive overview of current pharmacologic options.
    • Further research may be needed to expand therapeutic choices for horses.