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Published on: March 27, 2018
Predictors and outcomes of cardiac complications following elective coronary bypass grafting
M Charlson1, K H Krieger, J C Peterson
1Department of Medicine, Weill Medical College, Cornell University, New York, NY 10021, USA.
Insights
Preoperative diuretics and longer cross-clamp times predict cardiac complications in coronary artery bypass graft (CABG) surgery. Most patients with complications improved quality of life within six months.
Area of Science:
- Cardiology
- Cardiac Surgery
- Health Outcomes Research
Background:
- Coronary artery bypass graft (CABG) surgery is a common procedure.
- Identifying predictors of cardiac complications is crucial for patient management.
- Understanding the impact of complications on quality of life is important.
Purpose of the Study:
- To identify predictors of major and minor cardiac complications in elective CABG patients.
- To assess the relationship between cardiac complications and quality of life/symptoms at 6 months post-surgery.
Main Methods:
- Prospective cohort study of 248 elective CABG patients.
- Data collected preoperatively, intraoperatively, and at 6 months postoperatively.
- Multivariable logistic regression used to identify predictors of major cardiac complications.
Main Results:
- The combined rate of major and minor cardiac complications was 9.7%.
- Preoperative diuretic use (p = .01) and increased cross-clamp time (p = .006) predicted major cardiac complications.
- Patients with postoperative cardiac complications had a higher rate of worsening symptoms at 6 months (19%) compared to those without (8%, p = .03).
Conclusions:
- Preoperative diuretic use and longer cross-clamp times are significant risk factors for cardiac complications after CABG.
- Despite complications, most patients experience improved function and symptoms by 6 months post-surgery.
Abstract:
Our objective was to determine the predictors of cardiac complications among a cohort of elective coronary artery bypass graft (CABG) surgery patients and to determine the relationship of such complications to subsequent quality of life and symptoms. A total of 248 patients were enrolled and 237 completed 6 month follow-up. The combined rate of both major and minor cardiac complications was 9.7% (n = 24). Patients in this study were evaluated preoperatively, monitored intraoperatively, followed immediately postoperatively and at 6 months. Major cardiac complications accounted for 3.6% (n = 9) and minor complications for 6% (n = 15). Using multivariable logistic regression analysis, the predictors of major cardiac complications were receiving diuretics preoperatively (p = .01) and increased time during cross-clamping (p = .006). At 6 months after surgery, 19% of the patients with postoperative cardiac complications experienced worsening of symptoms, in contrast to only 8% of those without cardiac complications (p = .03). We concluded that patients who were on preoperative diuretics and those who had longer cross-clamp times were at higher risk of cardiac complications. The majority of patients who had acute cardiac complications had improved function and symptoms at 6 months postoperatively.
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