Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Delayed reverberation through time windows as a key to cerebellar function.

W M Kistler, J Leo van Hemmen

    Biological Cybernetics
    |December 11, 1999
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mathematization of nature: how it is done.

    Biological cybernetics·2021
    Same author

    Active tympanic tuning facilitates sound localization in animals with internally coupled ears.

    Hearing research·2020
    Same author

    Modeling underwater hearing and sound localization in the frog <i>Xenopus laevis</i>.

    The Journal of the Acoustical Society of America·2018
    Same author

    Reflections on biological cybernetics: past, present, prospects.

    Biological cybernetics·2018
    Same author

    Animals and ICE: meaning, origin, and diversity.

    Biological cybernetics·2016
    Same author

    Internally coupled ears: mathematical structures and mechanisms underlying ICE.

    Biological cybernetics·2016

    This study models the cerebellum

    Area of Science:

    • Neuroscience
    • Computational Neuroscience
    • Systems Neuroscience

    Background:

    • Presents a functional model of the cerebellum, incorporating cerebellar cortex, inferior olive, deep cerebellar nuclei, and brain stem nuclei.
    • Focuses on time coding, describing neural activity via postsynaptic potentials, synchronous action potentials, and propagation delays.

    Discussion:

    • Golgi cells act as gates, creating precise time windows for granule cell firing, organizing activity into discrete 'time slices'.
    • Rebound firing in cerebellar nuclei cells generates reverberation of Purkinje cell activity back to the cerebellar cortex via cerebellar-reticular projections.

    Key Insights:

    • Computer simulations demonstrate that network reverberation and synaptic plasticity enable learning, storage, and recall of spatio-temporal patterns.

    Related Experiment Videos

  • Climbing fiber spikes function as synchronization and teacher signals, not error signals, arising from olivary neuron oscillations and network reverberation.

    • Outlook:

    • The model offers experimental predictions and new explanations for climbing fiber spike synchronicity and cerebellar timing tasks.
    • Provides a novel framework for understanding how the cerebellum processes timing information over hundreds of milliseconds.