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Gene discovery using the maize genome database ZmDB.

X Gai1, S Lal, L Xing

  • 1Department of Zoology, Iowa State University, Ames, IA 50011-3260, USA.

Nucleic Acids Research
|December 11, 1999
PubMed
Summary
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The Zea mays DataBase (ZmDB) offers a comprehensive resource for maize genetic data, including sequences and phenotypes. It facilitates efficient gene discovery through integrated analysis tools and data accessibility.

Area of Science:

  • Plant Genomics
  • Bioinformatics
  • Agricultural Science

Background:

  • Maize (Zea mays) is a vital global crop requiring extensive genetic research.
  • Large-scale collaborative projects have generated significant amounts of maize sequence, expression, and phenotype data.
  • Efficient data management and analysis tools are crucial for leveraging this information.

Purpose of the Study:

  • To establish a centralized repository and analysis platform for maize genetic data.
  • To provide tools for efficient gene discovery and analysis using available data.
  • To facilitate access to research materials generated by maize genetic projects.

Main Methods:

  • Development of the Zea mays DataBase (ZmDB) as a data repository.
  • Integration of data from transposon tagging and expressed sequence tag (EST) sequencing projects.

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  • Implementation of database search tools, external database links, and sequence analysis programs.

    • Main Results:

    • ZmDB provides access to a substantial collection of maize sequence, expression, and phenotype data, with ESTs forming the majority of the content.
    • Includes tools for spliced alignment and sequence inspection, enhancing gene discovery protocols.
    • Offers web-based ordering for research materials like DNA clones, mutant seeds, and microarrays.

    Conclusions:

    • ZmDB serves as an essential bioinformatics resource for the maize research community.
    • The integrated platform streamlines gene discovery and data analysis for Zea mays.
    • Facilitates the utilization of generated genetic resources for further crop improvement.