Related Experiment Video
Updated: Jul 30, 2026
09:34
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
NCBI's LocusLink and RefSeq.
D R Maglott1, K S Katz, H Sicotte
1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Nucleic Acids Research
|December 11, 1999
Summary
The National Center for Biotechnology Information (NCBI) launched LocusLink and RefSeq, new web tools for accessing gene information and reference sequences. These resources offer a unified view of human gene, transcript, and protein data.
Area of Science:
- Bioinformatics
- Genomics
- Molecular Biology
Background:
- Gene information retrieval is complex.
- Standardized reference sequences are crucial for research.
Purpose of the Study:
- Introduce LocusLink and RefSeq.
- Provide non-redundant gene-based information.
- Establish reference sequence standards.
Main Methods:
- Development of web-based resources.
- Integration of gene, transcript, and protein data.
- Focus on human genetic information.
Main Results:
- LocusLink and RefSeq facilitate gene information access.
- These resources provide standardized reference sequences.
- A non-redundant view of human genetic knowledge is achieved.
Conclusions:
- LocusLink and RefSeq enhance gene data accessibility.
- These NCBI resources support genomic research.
- Standardization of reference sequences improves data consistency.
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